S
D
SiO2
Si back gate
polymer
Vg
Vsd
biotin
streptavidin
Ploymer coated, biotin-immobilized device (approximately
50 streptavidins)
Polymer coated device without biotin
Ligand-receptor binding without
false positives
Response to biotinilated streptavidin
Detection
limit: 10 proteins