ssDNA immobilization approaches
1. Noncovalent anchoring
Aromatic
molecule binding, ssDNA thethering
2. Thiol attachment to gild nanoparticles
Au
nanoparticle deposition followed by thiol chemistry
3. Tethering to polymer coating
PEI
tethering, following our biotin immobilization approach
2 and 3 has been
tried for proteins but not for DNA